Pajisjet thar\u00ebse t\u00eb manikyrit t\u00eb thonjve, mund t\u00eb shkaktojn\u00eb mutacione q\u00eb shkaktojn\u00eb kancer t\u00eb l\u00ebkur\u00ebs dhe t\u00eb ndryshojn\u00eb ADN-n\u00eb. N\u00eb k\u00ebt\u00eb p\u00ebrfundim ka arritur nj\u00eb studim i fundit i publikuar n\u00eb \u201cNature Communications\u201d nga studiuesit e Universitetit t\u00eb Kalifornis\u00eb s\u00eb San Diego.<\/p>\n
Ata zbuluan se p\u00ebrdorimi i k\u00ebtyre pajisjeve q\u00eb l\u00ebshojn\u00eb rreze ultravjollc\u00eb (UV) mund t\u00eb \u00e7oj\u00eb n\u00eb vdekjen e qelizave dhe mutacione q\u00eb shkaktojn\u00eb kancer n\u00eb qelizat njer\u00ebzore.<\/p>\n
\u201cN\u00ebse shikoni m\u00ebnyr\u00ebn se si jan\u00eb paraqitur k\u00ebto pajisje, ato tregtohen si t\u00eb sigurta, pa asgj\u00eb p\u00ebr t\u2019u shqet\u00ebsuar. Por askush nuk i ka studiuar k\u00ebto pajisje dhe se si ato ndikojn\u00eb n\u00eb qelizat njer\u00ebzore n\u00eb nivelet molekulare dhe qelizore deri m\u00eb tani\u201d, tha Ludmil Alexandrov, profesor i bioinxhinieris\u00eb, mjek\u00ebsis\u00eb celulare dhe molekulare n\u00eb UC San Diego dhe autor i studimit.<\/p>\n
Duke p\u00ebrdorur tre linja t\u00eb ndryshme qelizore, keratinocitet e l\u00ebkur\u00ebs s\u00eb njeriut t\u00eb rritur, fibroblaste njer\u00ebzore dhe fibroblaste embrionale t\u00eb miut, studiuesit zbuluan se p\u00ebrdorimi i k\u00ebtyre pajisjeve t\u00eb pranishme n\u00eb sallonet e bukuris\u00eb, q\u00eb emetojn\u00eb UV p\u00ebr vet\u00ebm nj\u00eb seanc\u00eb 20-minut\u00ebshe \u00e7oi n\u00eb vdekjen e qelizave midis 20 dhe 30 p\u00ebr qind. Nd\u00ebrsa tre ekspozimet e nj\u00ebpasnj\u00ebshme prej 20 minutash shkaktuan vdekjen e 65-70 p\u00ebrqind t\u00eb qelizave t\u00eb ekspozuara.<\/p>\n
Ekspozimi ndaj drit\u00ebs UV gjithashtu shkaktoi d\u00ebmtime mitokondriale dhe t\u00eb ADN-s\u00eb n\u00eb qelizat e mbetura dhe rezultoi n\u00eb mutacione me modele q\u00eb mund t\u00eb v\u00ebrehen n\u00eb kancerin e l\u00ebkur\u00ebs tek njer\u00ebzit.<\/p>\n
\u201cNe pam\u00eb shum\u00eb gj\u00ebra. S\u00eb pari, pam\u00eb se ADN-ja d\u00ebmtohet. Pam\u00eb gjithashtu se disa nga d\u00ebmtimet e ADN-s\u00eb nuk riparohen me kalimin e koh\u00ebs dhe kjo \u00e7on n\u00eb mutacione pas \u00e7do ekspozimi me nj\u00eb thar\u00ebse thonjsh me xhel UV. S\u00eb fundi, pam\u00eb se ekspozimi mund t\u00eb shkaktoj\u00eb mosfunksionim mitokondrial, i cili gjithashtu mund t\u00eb rezultoj\u00eb n\u00eb mutacione shtes\u00eb. Ne pam\u00eb pacient\u00ebt me kancer t\u00eb l\u00ebkur\u00ebs dhe shohim ekzakt\u00ebsisht t\u00eb nj\u00ebjtat modele t\u00eb mutacioneve n\u00eb k\u00ebta pacient\u00eb q\u00eb u pan\u00eb n\u00eb qelizat e rrezatuara\u201d, tha Alexandrov.<\/p>\n
Nd\u00ebrsa rezultatet tregojn\u00eb efektet e d\u00ebmshme t\u00eb p\u00ebrdorimit t\u00eb k\u00ebtyre pajisjeve n\u00eb qelizat njer\u00ebzore, studiuesit paralajm\u00ebrojn\u00eb se duhet nj\u00eb studim afatgjat\u00eb epidemiologjik p\u00ebrpara se t\u00eb thuhet p\u00ebrfundimisht se p\u00ebrdorimi i k\u00ebtyre makinave \u00e7on n\u00eb nj\u00eb rrezik t\u00eb shtuar t\u00eb kancerit t\u00eb l\u00ebkur\u00ebs. Por rezultatet e studimit ishin t\u00eb qarta: P\u00ebrdorimi kronik i k\u00ebtyre makinave p\u00ebr tharjen e manikyrit \u00ebsht\u00eb i d\u00ebmsh\u00ebm p\u00ebr qelizat njer\u00ebzore.\/A2CNN\/<\/p>\n","protected":false},"excerpt":{"rendered":"
Pajisjet thar\u00ebse t\u00eb manikyrit t\u00eb thonjve, mund t\u00eb shkaktojn\u00eb mutacione q\u00eb shkaktojn\u00eb kancer t\u00eb l\u00ebkur\u00ebs dhe t\u00eb ndryshojn\u00eb ADN-n\u00eb. N\u00eb k\u00ebt\u00eb p\u00ebrfundim ka arritur nj\u00eb studim i fundit i publikuar n\u00eb \u201cNature Communications\u201d nga studiuesit e Universitetit t\u00eb Kalifornis\u00eb s\u00eb San Diego. Ata zbuluan se p\u00ebrdorimi i k\u00ebtyre pajisjeve q\u00eb l\u00ebshojn\u00eb rreze ultravjollc\u00eb (UV) mund […]<\/p>\n","protected":false},"author":1,"featured_media":139568,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":{"0":"post-139567","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-magazina"},"_links":{"self":[{"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/posts\/139567","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/comments?post=139567"}],"version-history":[{"count":0,"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/posts\/139567\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/media\/139568"}],"wp:attachment":[{"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/media?parent=139567"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/categories?post=139567"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/tags?post=139567"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}