Nj\u00eb klas\u00eb e re e imunoterapis\u00eb mund t\u00eb ofroj\u00eb shpres\u00eb p\u00ebr pacient\u00ebt me kancer q\u00eb nuk i p\u00ebrgjigjen trajtimeve ekzistuese, sugjeron hulumtimi.<\/p>\n
Studimi zbuloi se ila\u00e7i, i quajtur MOv18 IgE, zvog\u00ebloi nj\u00eb tumor tek nj\u00eb pacient me kancer ovarian dhe raportoi se ai u pranua mir\u00eb nga pacient\u00ebt.<\/p>\n
Shkenc\u00ebtar\u00ebt sugjerojn\u00eb se gjetjet e tyre mund t\u00eb hapin rrug\u00ebn p\u00ebr nj\u00eb ila\u00e7 krejt\u00ebsisht t\u00eb ri kund\u00ebr kancerit p\u00ebr njer\u00ebzit me kancer rezistent ndaj kimioterapis\u00eb.<\/p>\n
Studimi, nga studiues nga King\u2019s College London dhe Guy\u2019s dhe St Thomas\u2019 NHS Foundation Trust, dhe i financuar nga Cancer Research UK, testoi n\u00ebse nj\u00eb lloj antitrupi i quajtur imunoglobulina E (IgE) mund t\u00eb p\u00ebrdoret p\u00ebr t\u00eb trajtuar kancerin njer\u00ebzor.<\/p>\n
Imunoterapia funksionon duke stimuluar sistemin mbrojt\u00ebs natyror t\u00eb trupit p\u00ebr t\u00eb sulmuar kancerin.<\/p>\n
Ila\u00e7et ekzistuese t\u00eb antitrupave t\u00eb p\u00ebrdorura n\u00eb kancer i p\u00ebrkasin nj\u00eb lloji t\u00eb antitrupave t\u00eb quajtur IgG, por antitrupat IgE nuk jan\u00eb testuar m\u00eb par\u00eb te njer\u00ebzit.<\/p>\n
Antitrupat IgE evoluan p\u00ebr t\u00eb synuar parazit\u00ebt si krimbat dhe flukset, dhe antitrupat IgG p\u00ebrfshihen n\u00eb sulmin e baktereve dhe viruseve n\u00eb trup.<\/p>\n
\u201cIgE \u00ebsht\u00eb nj\u00eb form\u00eb krejt\u00ebsisht e re e terapis\u00eb me antitrupa, e cila ka treguar premtime t\u00eb m\u00ebdha n\u00eb k\u00ebt\u00eb prov\u00eb t\u00eb Faz\u00ebs I\u201d, tha autori kryesor Profesor James Spicer, profesor i mjek\u00ebsis\u00eb eksperimentale t\u00eb kancerit n\u00eb King\u2019s College n\u00eb Lond\u00ebr dhe konsulent n\u00eb onkologjin\u00eb mjek\u00ebsore n\u00eb Fondacionin NHS t\u00eb Guy dhe St Thomas.<\/p>\n
\u201cGjetjet tona tregojn\u00eb se ila\u00e7i tolerohej mir\u00eb te pacient\u00ebt dhe zvog\u00ebloi nj\u00eb tumor kanceroz n\u00eb nj\u00eb pacient me kancer ovarian. Rezultatet hapin rrug\u00ebn p\u00ebr zhvillimin e nj\u00eb klase krejt\u00ebsisht t\u00eb re t\u00eb ila\u00e7eve kund\u00ebr kancerit, p\u00ebr njer\u00ebzit me kancer rezistent ndaj kimioterapis\u00eb. Ekspertiza e imunologjis\u00eb n\u00eb laborator\u00ebt e King\u2019s College n\u00eb Lond\u00ebr na lejoi t\u00eb nd\u00ebrmarrim k\u00ebt\u00eb prov\u00eb t\u00eb nj\u00eb forme krejt\u00ebsisht t\u00eb re t\u00eb terapis\u00eb me antitrupa\u201d, u shpreh Profesor James Spicer.<\/p>\n
Bashkautorja Sophia Karagiannis, profesoresh\u00eb e imunologjis\u00eb dhe imunoterapis\u00eb p\u00ebrkthimore t\u00eb kancerit n\u00eb King\u2019s College n\u00eb Lond\u00ebr, tha: Imunoterapia ka treguar nj\u00eb potencial t\u00eb madh koh\u00ebt e fundit, por ka ende njer\u00ebz me kancer q\u00eb nuk i p\u00ebrgjigjen terapis\u00eb konvencionale. Kjo prov\u00eb bazohet n\u00eb pun\u00ebn ton\u00eb t\u00eb m\u00ebparshme n\u00eb biologjin\u00eb e IgE, duke p\u00ebrfshir\u00eb eksperimentet n\u00eb laborator q\u00eb sugjerojn\u00eb se IgE, mund t\u00eb jet\u00eb nj\u00eb trajtim efektiv q\u00eb mund t\u00eb ofroj\u00eb p\u00ebrfitime shtes\u00eb p\u00ebr t\u00eb plot\u00ebsuar ato t\u00eb antitrupave t\u00eb IgG t\u00eb vendosura n\u00eb klinik\u00eb.<\/p>\n
Nd\u00ebrsa jemi ende n\u00eb faz\u00ebn e hershme t\u00eb provave, hapat tan\u00eb t\u00eb ardhsh\u00ebm do t\u00eb jen\u00eb t\u00eb vler\u00ebsojm\u00eb IgE n\u00eb grupe m\u00eb t\u00eb m\u00ebdha dhe t\u00eb ndryshme pacient\u00ebsh dhe t\u00eb vazhdojm\u00eb t\u00eb studiojm\u00eb se si antitrupat IgE, jan\u00eb n\u00eb gjendje t\u00eb zgjojn\u00eb sistemin imunitar t\u00eb pacientit p\u00ebr t\u00eb luftuar kancere t\u00eb ndryshme.<\/p>\n
Antitrupi MOv18 IgE u zbulua dhe u zhvillua n\u00eb King\u2019s College n\u00eb Lond\u00ebr, n\u00eb bashk\u00ebpunim me IRCCS Instituto Nazionale dei Tumori, Milano, Itali dhe u testua klinikisht nga Qendra Eksperimentale e Mjek\u00ebsis\u00eb s\u00eb Kancerit me baz\u00eb n\u00eb Spitalin Guy.<\/p>\n
Studimi, i financuar dhe i sponsorizuar nga Cancer Research UK, \u00ebsht\u00eb publikuar n\u00eb Nature Communications.<\/p>\n","protected":false},"excerpt":{"rendered":"
Nj\u00eb klas\u00eb e re e imunoterapis\u00eb mund t\u00eb ofroj\u00eb shpres\u00eb p\u00ebr pacient\u00ebt me kancer q\u00eb nuk i p\u00ebrgjigjen trajtimeve ekzistuese, sugjeron hulumtimi. Studimi zbuloi se ila\u00e7i, i quajtur MOv18 IgE, zvog\u00ebloi nj\u00eb tumor tek nj\u00eb pacient me kancer ovarian dhe raportoi se ai u pranua mir\u00eb nga pacient\u00ebt. Shkenc\u00ebtar\u00ebt sugjerojn\u00eb se gjetjet e tyre mund […]<\/p>\n","protected":false},"author":1,"featured_media":155228,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":{"0":"post-155227","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-shendetesi"},"_links":{"self":[{"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/posts\/155227","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/comments?post=155227"}],"version-history":[{"count":0,"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/posts\/155227\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/media\/155228"}],"wp:attachment":[{"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/media?parent=155227"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/categories?post=155227"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/radiostargjilan.com\/web\/wp-json\/wp\/v2\/tags?post=155227"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}